Nigella sativa: A Potent Secondary Metabolite

Nigella sativa, commonly known as black seed possess an extensive pharmacological potential and has emerged a wonder herb with rich historical religious background. For decades, people all over the world have utilised N. sativa seeds oil to treat wide range of illnesses. Because was stated cure for every illness except death in one Prophetic hadiths, it is regarded by Muslims greatest forms curative medicine accessible. Tibb-e-Nabwi (Prophetic Medicines) another place where regular use advised. In-depth research been done on chemical components sativa. It primarily comprises fixed (24.76-40.35%), volatile (0.5-1.6%), alkaloids, saponins, other substances minute amounts. Thymoquinone seems be responsible potent activities [2]. are frequently used illnesses, including bronchitis, asthma, diarrhoea, rheumatism, skin conditions. also stimulate immune system, fight parasite infections, act digestive aid anti-diarrheal [3].
 demonstrated that both thymoquinone, prevent liposomes from undergoing non-enzymatic lipid peroxidation. shown administering extract rats up 12 weeks causes changes haemogram, increase packed cell volume (PCV) haemoglobin (Hb), well decrease plasma concentrations glucose, cholesterol, triglycerides. The extremely low level toxicity, which distinguishes [4] them. Following topical application, two occurrences contact dermatitis documented. or its does not substantial negative impact liver kidney function [5]. would seem cytoprotective antioxidant properties their various inflammatory mediators, may connected positive effects use.
 Exploring cellular molecular mechanisms action active seed, particularly TQ, health diseases require urgently further using human animal models.